THE USE OF INTERIM DATA AND DATA MONITORING COMMITTEE RECOMMENDATIONS IN RANDOMIZED CONTROLLED TRIAL REPORTS: FREQUENCY, IMPLICATIONS AND POTENTIAL SOURCES OF BIAS

The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias

Abstract Background Interim analysis of accumulating trial data is important Vitamin D to protect participant safety during randomized controlled trials (RCTs).Data Monitoring Committees (DMCs) often undertake such analyses, but their widening role may lead to extended use of interim analysis or recommendations that could potentially bias trial res

read more

Considerations and recommendations for collaborative research networks in epidemiology: Lessons learned from the diabetes LEAD Network

Multi-site and multi-organizational teams are increasingly common in epidemiologic research; however, there is a lack of standards or best practices for achieving 136 success in collaborative research networks in epidemiology.We summarize our experiences and lessons learned from the Diabetes Location, Environmental Attributes, and Disparities (LEAD

read more

Does trichomoniasis, the most common nonviral sexually transmitted disease in Saudi Arabia and the globe, get all the focus it requires?

One of the sexually transmitted parasitic diseases (STPDs) is trichomoniasis.It is infectious disease, spreads through unprotected sexual intercourse, and may cause a variety of reproductive health problems in both men and women.There is a serious knowledge gap about trichomoniasis, which could have increased the rate of infection and Trichomonas v

read more